Distribution of 5-HT1A receptors in depression

In depression the density of 5-HT1A receptors is altered compared with the normal brain. The 5-HT1A receptor density is increased in the hippocampus and medial temporal cortex, while the density of these receptors is reduced compared with normal in the cerebellum, basal ganglia and prefrontal cortex.

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References

Psychopharmacol Bull 1994;30(1):39–43.

Biol Psychiatry 1999; 46(10):1375–87.