Distribution of 5-HT1A receptors in the normal brain

There are seven sub-types of 5-HT receptor and the 1A subtype is widely expressed throughout the brain. The highest levels of this sub-type are found in the hippocampus and medial temporal cortex, with slightly lower levels in the pre-frontal cortex. Low levels of 5-HT1A are found in the basal ganglia.

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References

Brain Res 1994;658(1-2):55–9

J Nucl Med 2000;41(11):1830–5.

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