The molecular genetics of bipolar disorder – the X chromosome
Genetic linkage studies have indicated distinct regions on several chromosomes that may be associated with a family history of bipolar disorder. Two regions of interest, Xq22.1 (DNA marker DXS6789) and Xq24-27.1, have been identified on the long arm of the X chromosome that may lead to an increased risk of bipolar disorder. The precise genes associated with these regions and their functions in the brain have not been identified.
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References
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