The molecular genetics of bipolar disorder – chromosome 16

Although no single gene has been identified in the inheritance of bipolar disorder, genetic linkage studies have indicated distinct regions on several chromosomes that may be associated with a family history of the disorder. A region on the short arm of chromosome 16 (16p) has been identified that may lead to an increased risk of bipolar disorder. The precise genes associated with this region and their functions in the brain have not been identified.

Click the image to view high resolution version

References

Curr Psychiatry Rep 2000;2:147–157.

Neuroscience Research 2001;4:105–113.

Br J Psychiatry Suppl 2001;41:s128–133.