Regions of the brain implicated in OCD

In obsessive compulsive disorder (OCD) there is abnormal metabolic activity in the orbitofrontal cortex, the anterior cingulate/caudal medial prefrontal cortex, and the caudate nucleus. Activity within this cortico-basal ganglia network is increased at rest compared with controls. During provocation of symptoms this activity is accentuated: it is reduced following successful treatment.

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References

Neuron 2000:28:343–347.

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